Water & Scutellaria Baicalensis (Skullcap) Root Extract & Astragalus Membranaceus (Milkvetch) Root Extract & Rehmannia Glutinosa (Chinese Foxglove) Root Extract & Magnolia Officinalis (Magnolia) Bark Extract
Volugro BCR is a synergy of botanical extracts that promote the health and wellness of the scalp. The unique complex nourishes the scalp and creates a proper environment to encourage hair fullness and reduce the occurrence of hair-fall.
Volugro BCR is developed with BCR’s unique extraction technology that uses plant derived enzymes to simplify complex botanical actives so they are more easily absorbed by the skin. Thus, saving the skin energy to be used for cellular communication and self-repair for overall wellness. Highly effective proprietary enzymes allow for the use of minimal plant material with maximum yield of beneficial nutrients. As such, BCR’s BioTransformed extracts are sustainable, eco-friendly and cost effective.
Scutellaria Baicalensis is commonly known as skullcap or “helmet flower,” alluding to its resemblance to miniature medieval helmets. It is an important herb in traditional Chinese medicine (TCM), and baicalin, the active flavonoid isolated from the plant, is known for many biological activities, including anti-inflammatory and antioxidant properties. Studies report that baicalin promotes healthy hair growth by increasing the size of both the follicle and the hair fiber, as well as activating a signaling pathway that facilitates cell differentiation critical to inducing hair follicle formation.
Apoptosis (cell death) of hair keratinocytes with premature termination of hair follicle growth induces several types of hair loss. Astragaloside (a major biocomponent of Astragalus) has been shown to inhibit apoptosis in hair keratinocytes and promote hair regrowth. The combination of Astragalus Membranaceus and Rehmannia Glutinosa have been shown to upregulate important cellular growth factors with notable anti-inflammatory properties and improved intercellular communication that is supportive to healthy scalp skin cells. Rehmannia Glutinosa also has high free radical scavenging activity, and its active components have been demonstrated to suppress inflammatory responses elicited by advanced glycation end products.
A chemical investigation of the cortex of Magnolia Officinalis (Magnolia bark extract) reveals several major lignans such as honokiol and magnolol, which have notable anti-inflammatory properties and benefits focused on TGF-B cell cycle arrest to decrease hair loss.
In vitro testing shows that Volugro BCR downregulates the expression of proteins destructive to the extracellular matrix (MMP-1) and upregulates an essential protein in the basement membrane (LAMA-1) as well as two important cellular growth factors (TGF-β and VEGF). This activity helps to support cellular function and communication, and nutrition of the scalp skin cells to prevent aging and hair loss.